Arithmetic Operations in Multi-Valued Logic

This paper presents arithmetic operations like addition, subtraction and multiplications in Modulo-4 arithmetic, and also addition, multiplication in Galois field, using multi-valued logic (MVL). Quaternary to binary and binary to quaternary converters are designed using down literal circuits. Negation in modular arithmetic is designed with only one gate. Logic design of each operation is achieved by reducing the terms using Karnaugh diagrams, keeping minimum number of gates and depth of net in to consideration. Quaternary multiplier circuit is proposed to achieve required optimization. Simulation result of each operation is shown separately using Hspice.Comment: 12 Pages, VLSICS Journal 201

Design and Implementation of Image Compression Encoder using Orthogonal Approximation DCT

Image Compression is usually carried out using discrete cosine transform (DCT) because compressed image using DCT will take less memory to store the image and quality of the image will be good compared JPEG and HEVC. But, in this work an attempt is made to achieve compression using Approximation DCT (ADCT). ADCT is useful for reducing its computational complexity without affecting its coding performance. It provides better image and video compression compared to the DCT. ADCT is orthogonal and it has lower structural complexity compared to DCT. The unique feature of the ADCT is that it could be configured for the computation of the 32 point ADCT or for parallel computation of two16 point ADCTs or four 8 points ADCTs. It has many advantages in terms of orthogonality, structural simplicity and lower computational complexity. The proposed ADCT is implemented using Verilog and Simulated by ModelSim and synthesized by Xilinx ISE 9.1i. Results are compared with 16 point ADCT with 16 point DCT implementation. The target device is XC5vtx330t-2ff1738. The 16 point ADCT implementation results in a saving of 28.37% IOBs and 63% of LUTs, compared to existing 16 point DCT implementation

Deploying Health Monitoring ECU Towards Enhancing the Performance of In-Vehicle Network

Electronic Control Units (ECUs) are the fundamental electronic building blocks of any automotive system. They are multi-purpose, multi-chip and multicore computer systems where more functionality is delivered in software rather than hardware. ECUs are valuable assets for the vehicles as critical time bounded messages are communicated through. Looking into the safety criticality, already developed mission critical systems such as ABS, ESP etc, rely fully on electronic components leading to increasing requirements of more reliable and dependable electronic systems in vehicles. Hence it is inevitable to maintain and monitor the health of an ECU which will enable the ECUs to be followed, assessed and improved throughout their life-cycle starting from their inception into the vehicle. In this paper, we propose a Health monitoring ECU that enables the early trouble shooting and servicing of the vehicle prior to any catastrophic failure.Comment: 7 pages, 4 figures, FCST 201

Shock stand-off distance visualization in hypersonic shock tunnel using electrical discharge technique

Visualization of the detached shock wave that forms ahead of a blunt body flying at hypersonic Mach number using electrical discharge technique is a simple and convenient technique to measure the stand-off distance experimentally in an hypersonic shock tunnel. In this technique a thin sheet of electrical discharge generated between a point electrode attached to the wall of the test section and a line electrode embedded on the model surface reveals the position of the shock wave around the body in hypersonic flow. In this paper we present the details of this technique and sample results obtained for typical body shapes tested in HST2 shock tunnel at a freestream Mach number of 5.75. The detached shock waves in front of the test models are clearly visualized using this technique. The shock stand-off distance estimated based on the numerical results for a large angle blunt cone obtained using a commercial CFD code match well with the experimentally measured value. These results clearly demonstrate the suitability of the electrical discharge technique for visualizing the flowfields in hypersonic testing facilities having very short test time

Genotypic capacity of post-anthesis stem reserve mobilization in wheat for yield sustainability under drought and heat stress in the subtropical region

Wheat productivity is severely affected by drought and heat stress conditions worldwide. Currently, stem reserve mobilization (SRM) is receiving increased attention as a trait that can sustain wheat yields under adverse environments. However, the significance of SRM in sustaining wheat yields under drought and heat stress conditions remains uncertain in the tropical climate of Indo-Gangetic Plain region. Therefore, this study aimed to investigate genotypic variations in SRM in wheat and their influence on yield sustainability under drought and heat stress environments. The experiment was designed in an alpha-lattice layout, accommodating 43 genotypes under four simulated environments [timely sown and well irrigated (non-stress); timely sown and water-deficit/drought stress; late-sown and well-irrigated crop facing terminally high temperature; and late-sown and water-deficit stress (both water-deficit and heat stress)]. The water-deficit stress significantly increased SRM (16%–68%, p < 0.01) compared to the non-stress environment, while the heat stress conditions reduced SRM (12%–18%). Both SRM and stem reserve mobilization efficiency exhibited positive correlations with grain weight (grain weight spike−1) under all three different stress treatments (p < 0.05). Strong positive correlations between stem weight (at 12 days after anthesis) and grain weight were observed across the environments (p < 0.001); however, a significant positive correlation between stem weight and SRM was observed only with stress treatments. Results revealed that the SRM trait could effectively alleviate the impacts of water-deficit stress on yields. However, the SRM-mediated yield protection was uncertain under heat stress and combined water-deficit and heat stress treatments, possibly due to sink inefficiencies caused by high temperature during the reproductive period. Defoliated plants exhibited higher SRM than non-defoliated plants, with the highest increment observed in the non-stress treatment compared to all the stress treatments. Results revealed that wider genetic variability exists for the SRM trait, which could be used to improve wheat yield under drought stress conditions

Single-dose pharmacokinetics of isoniazid and rifampicin in patients with chronic renal failure

The pharmacokinetics of Isoniazid and Rifampicin were studied in 18 patients with mild or moderate renal failure (creatinine clearance : 10.1-50.0 ml/min) and 17 patients with severe renal failure (creatinine clearance < 10.0 ml/min) and the findings compared with those in 16 healthy subjects. The renal excretion of Isoniazid, Acetylisoniazid, Rifampicin and Dcsacetylrifampicin was severely inhibited in patients with renal failure. Plasma Rifampicin and Isoniazid concentrations in rapid acetylators were similar in healthy subjects and both the groups of patients. In slow acetylators, plasma Isoniazid concentrations and exposure (AUC) and half-life of the drug, calculated on the basis of these concentrations were appreciably higher in patients than in healthy subjects (P < 0.01); the mean values in the two groups of patients were, however, similar. The correlations between plasma creatinine or creatinine clearance and peak concentration, exposure or half-life of Isoniazid were poor (r < 0.28) in the slow acetylators. These findings suggest that in patients with renal failure, it is not necessary to reduce dosage of Rifampicin or of Isoniazid in rapid acetylators but advisable in respect of Isoniazid in slow acetylators to lessen the risk of toxic reactions

Pharmacokinetics of isoniazid and rifampicin in patients with renal failure undergoing continuous ambulatory peritoneal dialysis (CAPD) Running Head : Pharmacokinetic of INH & RMP in renal failure (CAPD)

The pharmacokinetics of isoniazid (INH) and rifampicin (RMP) was determined in 22 renal failure patients, 11 each with low and high membrane permeabilities (LMP and HMP) undergoing Continuous Ambulatory Peritoneal Dialysis (CAPD). Blood samples were collected at different time points following oral administration of INH and RMP. Estimations of INH and RMP in blood were carried out by standard procedures and certain pharmacokinetic variables were calculated based on their concentrations in blood. The INH inactivation status was determined based on salivary levels of INH. The pharmacokinetic variables of INH and RMP did not differ significantly between LMP and HMP groups. The study results suggest that renal failure patients on CAPD may not require reduction in the dosage of RMP or INH in rapid acetylators. Slow acetylators might require dose reduction of INH. Determination of INH inactivation status is important when patients with renal failure and tuberculosis are treated with INH-containing regimens

Acetylator status influences bioavailability of isoniazid in patients with advanced HIV disease

Patients with advanced HIV disease may exhibit malabsorption of anti-tuberculosis(TB) drugs. We evaluated the effect of isoniazid (INH) acetylator status on the bioavailability of INH in HIV-infected patients with and without tuberculosis, based on urinary excretion of the drug. Estimation of INH in urine collected up to 8 hours after oral administration of 300 mg INH were undertaken in 23 TB, 40 HIV and 26 HIV-TB patients. Determination of acetylator status of all these patients was also carried by differential estimations of INH and acetyl INH in urine collected between 5 and 6 hours after oral administration of 300 mg INH. Both slow and rapid acetylators in HIV and HIV-TB groups had significantly lower concentration of INH in urine compared to TB patients. The percent decrease in urinary excretion of INH was significantly higher in rapid than in slow acetylators, when compared to the corresponding TB patients. Acetylator status has an impact on the bioavailability of INH. Malbsorption in patients with advanced HIV disease may lead to decreased bioavailability of INH, particularly in rapid acetylators. Urinary estimation of INH provides reliable information on the bioavailability of the drug

Advanced Automata Minimization

We present an efficient algorithm to reduce the size of nondeterministic Buchi word automata, while retaining their language. Additionally, we describe methods to solve PSPACE-complete automata problems like universality, equivalence and inclusion for much larger instances (1-3 orders of magnitude) than before. This can be used to scale up applications of automata in formal verification tools and decision procedures for logical theories. The algorithm is based on new transition pruning techniques. These use criteria based on combinations of backward and forward trace inclusions. Since these relations are themselves PSPACE-complete, we describe methods to compute good approximations of them in polynomial time. Extensive experiments show that the average-case complexity of our algorithm scales quadratically. The size reduction of the automata depends very much on the class of instances, but our algorithm consistently outperforms all previous techniques by a wide margin. We tested our algorithm on Buchi automata derived from LTL-formulae, many classes of random automata and automata derived from mutual exclusion protocols, and compared its performance to the well-known automata tool GOAL.Comment: 15 page